The prevalence of drugs abuse abundance and its socio-mental outcomes calls a more comprehensive research than before. One of vulnerable groups who are under the influence of drugs are students, it raises in scale among those who find the drugs more accessible mainly due to their jobs. Bringing this fact into consideration, the researchers gave special attention to Mashad University Students in the second semester. A questionnaire was applied including some information about their ages, sexes, marital status, residing area, level of credits and the kind of drug used by them. Among 1126 distributed questionnaires, 433 ones were completed and returned to the office. The information collected was analyzed by means of spss system and pointed to this fact that there is a significant relationship between sex and age indicators to drug abuse, more among men. But there was no relationship between level of credit, residing area, marital status, etc. to drug abuse.