Objectives: Disability has some medical, social and human rights dimensions. The social models of disability consider the issue mainly as a socially created problem and as a social outcome of a physical or mental impairment. And basically, put the subject as a matter of the full integration of individuals into society. Lack of life –opportunity and access to socio – political and economic structures leads towards a discrimination against and exclusion of the disabled persons. Thus disability is often associated with increased poverty and vulnerability and social exclusion. This article considers the information and data about disables in Iran and the policies which provide them with life – opportunity. Method: This study is a documentary one and is based on secondary data analysis. Data is collected from Behzisti institution and the center of Iran statistics. Data and statistics about the Population of disables and about some fields such as income (rate of pension), occipital, education are considered. Findings: Although, there are no accurate data and information about population of disables, according to census of the center of Iran statistics in 1385 and the estimation of Behzisti institution, the main kinds of disability are blinds and cronies psychopath. To be able to empower this population, a serious social action is necessary.Disability in case of lack of life- opportunity leads to social exclusion. The full integration of disables into society needs the social action to provide these opportunities. As in Iran there are still limitation in relation to information and data about the population of people with disabilities and disability itself. So there is a lack of accurate knowledge about disability and the degree of disabled people's needs to the serviced and opportunities. Disable face to insufficient support, unemployment and capability, deprivation, like education. Results: In the case of disregarding the needs of disables and their life- opportunity, the result will be their social exclusion. As in Iran disables are among the poorest and the most social excluded people, because of their low level of education, low income, serious problems in finding job and lack of financial sources in order to accomplish of comprehensive law to support disables rights.