Introduction: In recent decades advances in science and technology generate economic growth in many countries. Therefore, some countries which are relatively poor in terms of natural resources, by using modern knowledge and technology, have made a big jump in the national economy. This instrument in efforts to create new branches of economics, as is knowledge based economy. This article estimates knowledge base economy indicators for the provinces of Iran on statistics of 1386.

  Method: The estimation methodology for knowledge which is introduced by the World Bank, have been used. In addition to the World Bank methodology, we have also taken advantage of factor analysis method.

  Findings: The results have shown that 4 provinces such as Tehran, Esfehan, Yaz and Semnan being top in term of the indicators which mentioned. While some provinces like Sistan va Balochestan, Hormozgan and Azarbayjan Gharbi stood on the lower place.

  Conclusion: The results of this study have indicated that, in terms of indicators, in addition to being with lower ranking in the world, the domestic resources and the knowledge based economy indicators are not distributed properly.